Dracunculosis (guinea-worm disease):

Note the guinea-worm over the lateral malleolus. The female worm comes out to lay eggs in water. The surrounding swelling is due to secondary infection.

Dracunculosis or guinea-worm infestation is associated with drinking water from wells containing Cyclops. Following the ingestion of Cyclops, the female of the organism Dracunculus medinensis develops in the human body and finds its way into areas likely to come in contact with water, such as the lower limbs. At these sites, the worm’s uterus protrudes through the skin to lay eggs. The area is characterized by an ulcer and the thread-like worm is easily seen. Treatment comprises mechanical removal of the worm. Should the worm break in the process, severe cellulitis is inevitable. Oral diethyl carbamazine, metronidazole, and thiabendazole are useful.