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Identify the cutaneous lesions
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Identify the cutaneous lesions
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Identify the cutaneous lesions ---
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Forums  »  Open clinical  »  General clinical  »  Identify the cutaneous lesions

Identify the cutaneous lesions

posted at 24/12/2012 1:19 PM GMT on bmj.com
Posts: 3037
First: 27/3/2012
Last: 18/5/2013
Identify the cutaneous lesions ---


Re: Identify the cutaneous lesions

posted at 25/12/2012 7:40 PM GMT on bmj.com
Posts: 3037
First: 27/3/2012
Last: 18/5/2013

Fixed drug eruption:

The first two pictures show fixed drug eruption, simulating erythema multiforme; a few satellite lesions are seen but are not necessary for diagnosis. The lesions heal with pigmentation that gets darker with each recurrence, at the same site; hence, it is known as a fixed drug eruption. More thickening of the lesion is seen at the periphery in the second picture. Common sites are lips and genitals. A later phase of evolution is seen in the third picture with bulla formation. This also heals with pigmentation.

If vitamin C is administered in the early phase, the lesions are cured dramatically within twenty four hours, suggesting vitamin C deficiency as a predisposing factor.

Re: Identify the cutaneous lesions

posted at 25/12/2012 9:21 PM GMT on bmj.com
Posts: 154
First: 29/11/2010
Last: 19/5/2013
A question sir.

How much is the Topical Vitamin C effective in taking care of such lesions and will you go for L-Ascorbic acid or Ascorbyl Palmitate(Ester-C) or Magnesium Ascorbyl phosphate?


Thank you.



Re: Identify the cutaneous lesions

posted at 26/12/2012 4:38 AM GMT on bmj.com
Posts: 3037
First: 27/3/2012
Last: 18/5/2013
Vitamin-C administration magically absorbs the microvascular bleeding within 48 hours, if the lesions are fresh. Generally we do administer tablets of L-ascorbic acid, in the dosage of 500mg twice daily or 200mg thrice for five days, followed by 200mg once daily for one month. Vitamin C is the safest amongst all the medicines, the only side effects observed being sleep disturbances in higher doses and 'rebound scurvy' in the neonates if administered in high doses in pregnancy. Vitamin C is the only vitamin which is not produced in the human body. It is the most powerful reducing (antioxidant) agent.

Re: Identify the cutaneous lesions

posted at 26/12/2012 3:04 PM GMT on bmj.com
Posts: 154
First: 29/11/2010
Last: 19/5/2013
Thanks a lot sir.So, an oral administration is all that's required.

I was curious about topical application that is mentioned frequetly these days.

Re: Identify the cutaneous lesions

posted at 31/12/2012 12:04 PM GMT on bmj.com
Posts: 312
First: 2/6/2012
Last: 10/5/2013
drug eruptioni

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