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Are you a good Fundoscopist?
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Are you a good Fundoscopist?
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Alzheimer's disease ( AD ) is the most common cause of dementia.Over the last decades there has been a shift towards identifying early stages of AD which include mild cognetive disorders. Improved me
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Forums  »  Open clinical  »  General clinical  »  Are you a good Fundoscopist?

Are you a good Fundoscopist?

posted at 12/7/2012 11:00 PM BST on bmj.com
Posts: 279
First: 2/8/2010
Last: 5/6/2013

Alzheimer's disease ( AD ) is the most common cause of dementia.Over the last decades there has been a shift towards identifying early stages of AD which include mild cognetive disorders. Improved methods of screening and early detection are essential to identify  cognitively normal individuals who have high risk of developing AD. It has been found that biomarkers which include retinal changes could be detected 25 years before development of structural changes in the brain that lead to development of cognitive changes in AD

 The retina shares many features with the brain, including embryological origin, anatomical (such as microvascular bed) and physiological characteristics (such as blood-tissue barrier),
 
Visual and retinal abnormalities, including early manifestation of retinal Aβ plaque ( amyloid-β protein ) pathology, have been documented in AD patients, these retinal changes are consistent with brain pathology, and occur before clinical symptoms and signs development, Other retinal changes which can occur early, include decreased retinal nerve fibre thickness, and optic disc cupping and retinal microvascular abnormalities
 
Could we monitor retinal abnormalities early enough following glatiramer acetate prophylaxis, before development of AD ?

Re: Are you a good Fundoscopist?

posted at 15/7/2012 2:39 PM BST on bmj.com
Posts: 312
First: 2/6/2012
Last: 10/5/2013
higher AVR ratio and thinning of venule with ischemic retinopathy and microaneurysm is also found . age related macular degeration is also seen.

Re: Are you a good Fundoscopist?

posted at 15/7/2012 3:04 PM BST on bmj.com
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First: 29/4/2011
Last: 31/5/2013

The problem that we have run into in diabetes is the quality of the fundoscopic examination in the primary care setting.  While there is no question that a dilated pupil fundoscopic examination in the hands of an experienced physician is adequate and comparable to retinal photography read by an eye care specialist, such examinations are rare in primary care. Virtually all diabetes retinopathy screening guideline recommend either referral to an eye care specialist or retinal photographs. http://guideline.gov/syntheses/printView.aspx?id=23794

Certainly changes in visual acuity using Snellen charts should be part of primary care visits by the elderly.  Whether or not they can play a role in fundoscopic screening is questionable.

Re: Are you a good Fundoscopist?

posted at 15/7/2012 6:40 PM BST on bmj.com
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First: 2/6/2012
Last: 10/5/2013
pl. add to previous post, above changes may be found in alzheimer disease.

Re: Are you a good Fundoscopist?

posted at 15/7/2012 6:51 PM BST on bmj.com
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First: 7/5/2009
Last: 2/4/2013
I will ne honest.
The answer is NO

Re: Are you a good Fundoscopist?

posted at 16/7/2012 4:54 PM BST on bmj.com
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First: 2/8/2010
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  Early Ophthalmic changes in Alzheimer's disease include narrowing of the retinal veins
  Ref :-  Invest. Ophthalmol. Vis. Sci. May 2007 vol. 48 no. 5 2285-2289 

   Figure 1.

Retinal photographs of a control subject (left) and a patient with Alzheimer’s Disease (right). The retinal veins in the patient appear narrower than those in the control subject

Re: Are you a good Fundoscopist?

posted at 28/7/2012 8:48 PM BST on bmj.com
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First: 25/1/2012
Last: 28/7/2012
Actually the proposed early signs of AD are 1.Aspecific and 2.To be put in differential diagnosis with other common conditions in the age classes when AD starts.
Cognitive impairment is an earlier and better sign to be detected.
This doesn't mean that we have to give up examining eye fundus in our patients, primarily for DM and hypertensive ones but not only. 
Let's remember that mydriatic drops (tropicamide 0.5 or 1%) are essential to be used for carrying out a proper examination.

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