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Genetic Technique to Control Malaria Mosquito
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Genetic Technique to Control Malaria Mosquito
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Malaria affects more than 300 million people around the world every year, killing nearly 800,000 people, most of them children. For the past 10 years, researchers have been attempting in the laborator
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Genetic Technique to Control Malaria Mosquito

posted at 22/9/2012 6:51 AM BST on bmj.com
Posts: 3045
First: 27/3/2012
Last: 20/5/2013
Malaria affects more than 300 million people around the world every year, killing nearly 800,000 people, most of them children. For the past 10 years, researchers have been attempting in the laboratory to biologically alter the malaria mosquito, known as Anopheles gambiae, so it can’t breed and spread the parasitic illness, as well as several other diseases. 
An international team of scientists has developed a way to genetically modify the malaria mosquito so that it would be unable to transmit the disease to humans. Researchers say the method eventually might be used to control large populations of mosquitoes by releasing a small number of modified insects into the wild that could breed the trait into ensuing generations.
An article on genetic manipulation of the Anopheles mosquito for malaria control is published this week in the journal Nature.Researchers on Sunday reported initial signs of success from the first release into the environment of mosquitoes engineered to pass a lethal gene to their offspring, killing them before they reach adulthood.
But there are two major concerns 1. Is it not possible that the mosquitoes might mutate themselves? 2. Possible unintended effects on public health and the environment, because once genetically modified insects are released, they cannot be recalled.
Links: http://www.nytimes.com/2011/10/31/science/concerns-raised-about-genetically-engineered-mosquitoes.html?pagewanted=all
http://www.voanews.com/content/scientists-use-genetic-technique-to-control-malaria-mosquito-120395174/171454.html

Re: Genetic Technique to Control Malaria Mosquito

posted at 22/9/2012 12:00 PM BST on bmj.com
Posts: 322
First: 12/11/2010
Last: 20/5/2013
It is interesting how we get upset when we think something cute and cuddly might become extinct but celebrated when smallpox was eradicated. If you kill off the mosquitos what happens to the other animals that feed on them...

Re: Genetic Technique to Control Malaria Mosquito

posted at 22/9/2012 4:33 PM BST on bmj.com
Posts: 1285
First: 9/12/2011
Last: 22/5/2013
Tim is right,  On two fronts,  #1- The animals that eat mosqiotos will be affected,   and cause multiple cascades of problems in the food chain,   and just like Juraissic park the Movie,   like the mathematician said,   NATURE WILL FIND A WAY!     Nature will remutate the mosquito,  perhaps even causing something we did not intend.  Perhaps AIDS wa created by this,  we know MRSA and XDR TB are human creations,  IE-caused  by our problems.       Tinkering with nature is dangerous.   DuaneF

Re: Genetic Technique to Control Malaria Mosquito

posted at 22/9/2012 7:44 PM BST on bmj.com
Posts: 3045
First: 27/3/2012
Last: 20/5/2013
Thanks respected Tim & Duane for your valuable suggestions on hazards of genetic manipulations.
There should be another research focused on irradication of malaria.

Re: Genetic Technique to Control Malaria Mosquito

posted at 22/9/2012 8:13 PM BST on bmj.com
Posts: 322
First: 12/11/2010
Last: 20/5/2013
They have in fact testsed this technology in the wild on Grand Cayman as a method of preventing Dengue fever. It resulted in a claimed 80% drop in mosquito numbers in 2010 - but those figures are disputed. IN 2012 the experiment was declared a failure. It is also believed that the introduced mosquitoes escaped the infertility control ; as in Jurassic park.

Re: Genetic Technique to Control Malaria Mosquito

posted at 23/9/2012 1:29 PM BST on bmj.com
Posts: 3045
First: 27/3/2012
Last: 20/5/2013
Very interesting information Tim! I have seen the program recently on national geographic HD on the various research activities to control malaria. It was also an excellent one.

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