{macro question(showVoteTotal)}
    <div class="poll-question">
      {if keyType == "discussion"}
        <a href="/forums/?plckForumPage=ForumDiscussion&plckDiscussionId=${key}#forumPostTitle_1" title="View discussion">
          ${poll.Question}
        </a>
      {else}
        ${poll.Question}
      {/if}
      {if showVoteTotal}
        <span class="poll-votes">(${poll.TotalVotes} ${"vote"|pluralise:poll.TotalVotes})</span>
      {/if}
    </div>
  {/macro}
  <div class="slResults" {if !noVote}style="display:none;"{/if}>
    ${question(true)}
    <table class="slAnswerStats" cellpadding="0" cellspacing="0" border="0">
      {for answer in poll.Answers}
        <tr class="slAnswerStat slAnswerStat_${answer_index}">
          <td class="slAnswer">${answer.Answer}</td>
          <td class="slAnswerBarCell">
            <div class="slAnswerBar">
              <div class="slAnswerCount">${answer.NumberOfVotes} ${"vote"|pluralise:answer.NumberOfVotes} (${answer.PercentageStr}%)</div>
              <div class="slAnswerBarPercent" style="width: ${answer.Percentage}%;"></div>
            </div>
          </td>
        </tr>
      {/for}
    </table>
    {if !noVote}<div class="results"><a href="javascript:void(0);" class="slVoteLink">Go vote!</a></div>{/if}
  </div>

{if !noVote}
  <div class="slVote">
    <div class="slErrorText">You must select one answer before submitting your vote.</div>
    ${question(false)}
    <table class="slAnswers" cellspacing="0" cellpadding="0" border="0">
      {for answer in poll.Answers}
        {var answerId = poll.PollKey.Key + '.' + answer_index}
        <tr>
          <td class="slAnswerInput">
            <input type="radio" name="answers" value="${answer_index}" id="${answerId}"/>
          </td>
          <td class="slAnswerText">
            <label for="${answerId}">${answer.Answer}</label>
          </td>
        </tr>
      {/for}
    </table>
    <div style="clear: both; margin-left: 8px;">
      <div class="slSendAnswer"><input class="slVoteButton" type="button" value="Vote" /></div>
      <div class="results"><a href="javascript:void(0);" class="slResultsLink">View Results...</a></div>
    </div>
  </div>
  {/if}

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Intensive Glucose Lowering Increase Mortality in Type 2 Diabetics Independent of Hypoglycaemia.

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Diabetes

Intensive Glucose Lowering Increase Mortality in Type 2 Diabetics Independent of Hypoglycaemia.

Discuss any aspect of type I or type II diabetes mellitus here

Hello Fellows: A recent analysis of the ACCORD Study tried to figure out  if the increased mortality found in the patients under intensive glucose lowering treatment to a target HBA1C below 6.0

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Forums » Open clinical » Diabetes » Intensive Glucose Lowering Increase Mortality in Type 2 Diabetics Independent of Hypoglycaemia.

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Forums » Open clinical » Diabetes » Intensive Glucose Lowering Increase Mortality in Type 2 Diabetics Independent of Hypoglycaemia.

Intensive Glucose Lowering Increase Mortality in Type 2 Diabetics Independent of Hypoglycaemia.

posted at 24/11/2011 6:13 AM GMT on bmj.com

Joey Rio

Posts: 367
First: 13/4/2011
Last: 16/5/2012

Hello Fellows:

A recent analysis of the ACCORD Study tried to figure out if the increased mortality found in the patients under intensive glucose lowering treatment to a target HBA1C below 6.0 was related to increased episodes of Hypoglicaemia. No such relationship was found:

"Intensive glucose lowering (HbA1c target<6.0%) for people with type 2 diabetes increases mortality"

http://ebm.bmj.com/content/16/6/186.full.pdf

Conclusions from the above article:

Weight gain and other adverse effects of glucose lowering medications remain as possible explanations.

In practical terms, the very intensive glucose lowering used in ACCORD, targeting an HbA1c<6%, should not be used, and caution in targeting <7% should be exercised in the typical ACCORD patient – longer diabetes duration and significant CVD risk.

Any Comments or insights?

All Best,

Joey

New post Reply to this post

Re: Intensive Glucose Lowering Increase Mortality in Type 2 Diabetics Independent of Hypoglycaemia.

posted at 21/4/2012 7:55 PM BST on bmj.com

Dr. K. Ashutosh

Posts: 504
First: 27/3/2012
Last: 16/5/2012

Yes, I do agree that attempts to lower the glucose levels aggressively does raise the mortality rate in NIDDM patients.

New post Reply to this post

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Forums » Open clinical » Diabetes » Intensive Glucose Lowering Increase Mortality in Type 2 Diabetics Independent of Hypoglycaemia.

Intensive Glucose Lowering Increase Mortality in Type 2 Diabetics Independent of Hypoglycaemia.

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