New mechanism to control multiple sclerosis (MS)?
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New mechanism to control multiple sclerosis (MS)?
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A University of Adelaide researcher has published results that suggest a possible new mechanism to control multiple sclerosis (MS). An orally active drug that blocks the activity of the molecule PI3Kg
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New mechanism to control multiple sclerosis (MS)?
posted at 19/10/2012 10:11 PM BST
on bmj.com
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Posts: 3045
First: 27/3/2012 Last: 20/5/2013 |
A University of Adelaide researcher has published results that suggest a possible new mechanism to control multiple sclerosis (MS). An orally active drug that blocks the activity of the molecule PI3Kgamma at the first signs of disease onset. The drug even suppressed the development of EAE and reversed clinical signs of the disease. By blocking PI3Kgamma, we can reduce the activation of self-reactive immune cells, reduce the release of inflammation-inducing molecules from immune cells, and also result in a dramatic reduction in the movement of immune cells into the central nervous system. Future therapies for MS might target this molecule, which could very specifically dampen the damaging inflammation in the central nervous system. Link: http://www.adelaide.edu.au/news/news56741.html |
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