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Clinical evidence is completely absent, but some treatments have been associated with risks ( mal nutrition, hepatotoxity, electrolyte disturbances and colon perforation).
Of naturopaths in the USA 92% use some form of alternative detox. Apparently detox is popular and big business.
Rehabilitation physicians and other healthcare professionals often are affiliated to spa’s and wellness centers that offer detox-programs. They should be aware that this alternative detox is biologically not plausible, clinically unproven and potentially harmful